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Irbesartan General Information
Avapro (generic name: irbesartan; brand names include: Approvel / Aprovel/ Irovel / Karvea) is an angiotensin II receptor antagonist used mainly for the treatment of high blood pressure (hypertension).
Avapro is also indicated for the treatment of diabetic nephropathy with an elevated serum creatinine and proteinuria in patients with type 2 diabetes and high blood pressure. Cheap Avapro USA
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In people with type 2 diabetes and high blood pressure, Avapro is also prescribed to stave off damage to the kidneys, often delaying the need for dialysis and a kidney transplant. Cheap Quality Avapro Canada
Avapro may be used alone or in combination with other medicines
Antihypertensive drug, antagonist of angiotensin receptors II. It specifically and irreversibly blocks receptors of angiotensin which leads to diminishing of biological effects of angiotensin II. Angiotensin II effects include vasoconstriction and stimulating influence on excretion of aldosterone and activation of sympathetic nervous system. As a consequence arterial pressure diminishes and the heart does not have to work as hard to pump blood. It does not influence concentration or triglycerides, content of cholesterol, glucose, uric acid in blood plasma and excretion of uric acid with urine.
Dosage and direction
Initial dose is 150 mg and it can be increased up to 300 mg on necessity. In some cases as low chloride diet, treatment with certain diuretics and others initial dose size should be smaller. Avapro is taken once a day preferably at the same time.
Precautions
It should be administered with kidney or liver failure, congestive heart failure, after strong vomit or diarrhea and also during simultaneous treatment with potassium saving diuretics or medications containing potassium. This drug causes serious harm to unborn baby (possibly death) if it is administered and used during the last six months of pregnancy.
Contraindications
Pregnancy, infancy, hypersensitivity to Avapro.
Possible side effect
The most common side effects include diarrhea, abdominal pain or heartburn. In case you experience allergic reaction to the medication (fever, difficult breathing, hives) contact your doctor. Avapro can cause a condition that results in the breakdown of skeletal muscle tissue and then in kidney failure. Also call your doctor if you have muscle pain, tenderness, or weakness especially if you also have vomiting, and dark colored urine, difficult urination.
Recommendations for Avapro
Follow the directions for using this medicine provided by your doctor. Take Avapro exactly as directed.
Take Avapro tablets by mouth. Avapro is usually taken once a day with or without food.
Take your doses at regular intervals. Do not take your medicine more often than directed.
Continue to take Avapro even if you feel well. Do not stop taking Avapro without talking to your doctor.
No dosage adjustment is necessary in elderly patients, or in patients with hepatic impairment or mild to severe renal impairment.
If you miss a dose of Avapro, take the missed dose as soon as you remember it. However, if it is almost time for your next dose, skip the missed dose and continue your regular dosing schedule. Do not take a double dose to make up for a missed one.
Store your tablets at room temperature, away from excess heat and moisture.
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Irbesartan Precautions
Before taking Avapro, tell your doctor if:
you are allergic to any medicines;
you have or have ever had heart failure or kidney disease;
you are pregnant or breast-feeding.
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What Avapro Contains?
Active ingredient: irbesartan.